For the handling of patients with postsurgical hypoparathyroidism, the transplant of cells of human parathyroid has been tried.
The difficulties to establish this type of cultures have been to maintain cultures lasting in the long term and to maintain cultures
with normal endocrin function. A method of cellular inmortalization, described by Caviedes et al. exists that allows to maintain
human parathyroid cells with the capacity to proliferate without losing their differentiated functions. With this method of inmor-
talization it will be managed in the long term to establish a continuous parathyroid cellular line with normal endocrinal function,
defined as the capacity of normal secretion of paratohormona (PTH), as opposed to different extracellular calcium concentratio-
ns. We present de procedure and its in vitro results
Keywords:
Hipoparatiroidismo, Trasplante de Células, Enfermedades de las Paratiroides
Cabané T., P. ., Rossi F., R. ., Romero O., C. ., Oviedo C., S. ., Caviedes C., R. ., & Caviedes F., P. . (2006). Establecimiento de la primera línea celular de paratiroides humana. Revista Hospital Clínico Universidad De Chile, 17(1), pp. 13–9. https://doi.org/10.5354/2735-7996.2006.78419
