Betalactamic antibiotic are hydrolyzed by specific enzymes, named extended spectrum beta-lactamases of (ESBLs). They are encoded by a plasmid present in some bacteria strains. The presence of bacteria strains carr ying these plasmids is a Public Health problem affecting Hospitals and all the community. The aim of this work is to study the incidence ESBLs in patients hospitalized at the Clinical
Hospital of the University of Chile. During July-August of 2004 we studied a total of 238 different strains of bacteria, including Ecoli (184), K. pneumoniae(39) and K. oxytoca (15) using a specific test for ESBLs according to NCCLS 2004. We found and incidence of 10.3,
28.2 and 20% for E. coli, K. pneumoniae and K. oxytoca, respectively. E. coli was found mainly at the Surger y and Medicine Depart-
ment, and K. pneumoniae was found in others critical services of our Hospital. We could set up in our Laboratory a diagnostic
test to evaluate the presence and distribution of different ESBLs in the Clinical Hospital of the University of Chile.
Barrera, B. ., Canales, A. ., Martínez, P. ., Vidal , M., Sakurada, A., & Vial, M. J. . (2005). Incidencia de β-lactamasas de espectro extendido en el Hospital Clínico de la Universidad de Chile. Revista Hospital Clínico Universidad De Chile, 16(2), pp. 101–6. https://doi.org/10.5354/2735-7996.2005.78721
